Resin Infiltration Vs Self-Assembling Peptide (P11-4) in Treating White Spot Lesions

Patient/population: Patients that range from 7-14 years of age with with at least one non-cavitated WSL located on smooth surfaces of maxillary or mandibular permanent teeth and comparable in size, opacity, and whitish appearance. Intervention: I1: Self-Assembling Peptide (P11-4) I2: Self-Assembling Peptide (P11-4) with fluoride varnish Comparator Resin Infiltration Outcome: Primary outcome * Esthetic Improvement of white spot lesion Outcome measure: Photographic analysis Outcome measuring Device: Image analysis to calculate change in area ratio of WSL to the labial surface using Photoshop software. Outcome measuring unit: change in Percentage • Tooth remineralization 1. Outcome measure: International Caries Detection and Assessment System (ICDAS) score. Outcome measuring Device: Visual and Clinical examination by operator Outcome measuring Unit : Numerical score from 0-6 2. Outcome measure: Quantitative light Fluorescence score from WSL Outcome measuring Device: Diagnodent Pen Outcome measuring Unit: Numerical score from 0-99 Secondary outcome Outcome measure: Patient Satisfaction Outcome measuring Device Likert 5-point faces scale ranging from very sad to very happy Outcome measuring Unit :Numerical score from 1-5 Study design: Randomized clinical trial Time: 6 months