Severe Primary Hand Hyperhidrosis Treatment With Topical Administration of Victorhy

This is a Phase II, multicenter, randomized, double-blind, parallel group and vehicle-controlled study in which participants with severe primary hand hyperhidrosis will be randomly assigned (1:1:1) to one of the following arms: * Victorhy dose 1 * Victorhy dose 2 * Placebo (Vehicle gel) This study will evaluate the efficacy of Victorhy, a topical TTB gel, in patients with severe primary hand hyperhidrosis. This trial will also assess the quality of life of study participants, the rebound effect, and the pharmacokinetics of topical TTB gel. The study is intended to assess a formulation including two different doses of Victorhy (treatment groups), compared to placebo (control group) with the objective of determining the optimal therapeutic dose for use in severe hand hyperhidrosis. Objectives: Primary objective: To assess the efficacy of a topical TTB gel in patients with severe primary hand hyperhidrosis. Secondary objectives: * To assess the tolerability and safety of topical TTB gel * To determine the optimal therapeutic dose of topical TTB gel * To assess the quality of life of study participants * To assess the rebound effect