To Check Dermatological Safety of Test Products by 24 Hours Patch Test on Adult Healthy Human Subjects.

Exclusion Criteria

• •1\) Subject having skin irritation, blemishes, excessive hair, moles, pigmentation, pimples, marks (e.g. tattoos (within the previous 3 months), scars, sunburn), open wounds, cuts, abrasions, irritation symptoms or any dermatological condition on the test site(s) i.e. back that can interfere with the reading.
• •2\) Medication which may affect skin response and/or past medical history. 3) Subject having history of diabetes 4) Subject have history of mastectomy for cancer involving removal of lymph nodes within the past year, or treatment of any type of cancer within the last 6 months.
• •5\) Subject suffering from any active clinically significant skin diseases which may contraindicate.
• •6\) Subject having history of any skin diseases including eczema, atopic dermatitis or active cancer.
• •7\) Participation in any patch test for irritation or sensitization within the last four weeks.
• •8\) Subject having history of asthma or COPD (Chronic obstructive pulmonary disease).
• •9\) Use of any: i. Prescribed or over-the-counter (OTC) anti-inflammatory drug within five (5) days prior to application.
• •ii. Antihistamine medication or immunosuppressive drugs within seven (7) days prior to first patch application.
• •iii. Systemic or topical corticosteroids at patch site within four (4) weeks of test product application (steroidal nose drops and/or eye drops are permitted) 10) Topical drugs used at application site. 11) Subject with Self-reported Immunological disorders such as HIV positive, AIDS and/or systemic lupus erythematous.
• •12\) Individual who has a medical condition or is taking or has taken a medication which, in the Investigator's judgment, makes the subject ineligible or places the subject at undue risk.
• •13\) Subject with known allergy or sensitization to medical adhesives, bandages. 14) Participation in other patch study simultaneously.