A Non-interventional, International, Multicentre Clinical Research Study to Build the Largest Collection of Multimodal Data (Including Clinical Data, Imaging Data and Omics Data) in Oncology
Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
OWKIN
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. That the patient was over the age of 18 when the sample was taken/consented to.
2. Availability of patient informed consent or non-opposition form to perform exploratory research matching at least one of the MOSAIC objectives (unless authorisation is granted by the local Institutional Review Board / Independent Ethics Committee (IRB/IEC) for the use of samples in the study according to local regulations and law).
3. Have a confirmed diagnosis based on international criteria for the relevant tumor type.
4. Confirmed formalin fixed and paraffin embedded (FFPE) tissue availability to generate at least the 3 core data modalities, and preferentially all MOSAIC data modalities.
5. Confirmed availability of associated clinical data.
6. Qualification of the paraffin tissue block meeting all of the following:
* Being of the expected tumor type
* For solid tumors (all cancer indications except diffuse large B cell lymphoma (DLBCL)): Tumor cell content ranging from 40% to 80% on an hematoxylin and eosin (H\&E) section within a specified area as dictated by the lab protocol specific to the technique utilized
* For DLBCL, a minimum of 80% of high grade component on an H\&E section within a specified area as dictated by the lab protocol specific to the technique utilized
* Wherever possible, the remaining tissue thickness must be over 125 micrometers (indicative range)
* Tumor sample must be \<10 years old
You may not be if
1\. Samples without a preserved tissue architecture, such as cytologies and cytoblocks.
Clareo Health | A Non-interventional, International, Multicentre Clinical Research Study to Build the Largest Collection of Multimodal Data (Including Clinical Data, Imaging Data and Omics Data) in Oncology
