About Pricing FAQs Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

A Study of SPY002-072 in Healthy Volunteers | Clinical Trials | Clareo Health

Back to clinical trial search

RECRUITINGPhase 1NCT06622070

A Study of SPY002-072 in Healthy Volunteers

This is a Phase 1, randomized, double-blind, placebo-controlled, single-dose, first in human safety, tolerability, and pharmacokinetic study of SPY002-072 in healthy participants.

Lead sponsor: Spyre Therapeutics, Inc.•1 U.S. locations•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Contacts

Medical Director, Clinical Development

CONTACT

617-651-5940 [email protected]

Sponsors

Lead Sponsor

Spyre Therapeutics, Inc.

Collaborators

Altasciences Company Inc.

Age

18 - 60 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Healthy men and women
•Willing and able to attend the necessary visits to the CRU, comply with all testing requirements, remain at the study site unit for the duration of the confinement period and return for the outpatient visits

Exclusion Criteria

•Participation in more than one cohort
•Evidence of clinically significant abnormality or disease
•Known history of illicit drug use or drug abuse, cannabis/cannabinoid use, harmful alcohol use (at the Investigator's discretion), alcoholism, and/or smoking or nicotine-containing product use within 3 months prior to the first dose of study agent
•History of severe allergic reactions or hypersensitivity
•Donation or loss of ≥ 1 unit of whole blood within 1 month prior to dosing

Related studies

Cardiopulmonary Responses to 6-Minute Stepper Test in Bronchiectasis Versus Healthy Controls

NCT06631261 · Bronchiectasis Adult, Healthy Controls Group - Age and Sex-matched

RECRUITINGPhase 1

A Study of Eltrekibart (LY3041658) in Healthy Participants

NCT07545590 · Healthy

RECRUITINGPhase 1

A Study of [18F]LY4214835 in Healthy Volunteers and Participants With Cancer

NCT07258836 · Neoplasms, Healthy

Collection of Data and Samples From Healthy Donors for Use in Translational Research

NCT00090662 · Healthy Volunteer

Bladder and Bowel Functions, Participation and Quality of Life in Children With Intellectual Disabilities

NCT07059858 · Intellectual Disability, Healthy Subjects

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: November 27, 2024Terms

Trial snapshot

StatusRECRUITING

PhasePHASE1

Enrollment56

Start dateNov 2024

Last updatedNov 27, 2024

Condition

Locations shown

Spyre Site 2

Cypress, California

Spyre Site 1

Montreal, Quebec

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 27, 2024Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions