Age

18–any

Sex

ALL

Healthy volunteers

Not accepted

Group 1
\- Adults ≥18 years with confirmed diagnosis of Crohn's disease
AND one of the following:
Gastrointestinal complaints such as diarrhea, bloody and/ or lose stools and abdominal pain, or obstructive symptoms.
Increased CRP (\>5 mg/L) and/or fecal calprotectin levels (\>250 mg/kg)
Active disease confiremed by endoscopy ( endoscopic SES-CD score \>3)
Active disease confirmed by IUS or MRI (bowel wall thickening, signs of active disease) Group 2
Adults ≥18 years with confirmed diagnosis of ulcerative colitis
AND one of the following:
Active disease confirmed by endoscopy (endoscopic Mayo score ≥ 2) or
Active disease confirmed by intestinal ultrasound (BWT \> 3 mm in atleast one bowel segment and atleast one other pathological IUS parameter)
Increased CRP (\>5 mg/L) and/or fecal calprotectin levels (\>250 mg/kg)

FAPi-PET Imaging of in Vivo Fibrosis in Inflammatory Bowel Disease Patients