Diagnostic Value of MRI-targeted Plus Index-lesion-ipsilaterally Systematic Biopsy for Biopsy-naive Men At Risk of Prostate Cancer

Exclusion Criteria

• •Prostate specific antigen\>20ng/ml；
• •the location of index lesion on prostate MRI is on the midline of the prostate and symmetrical on both sides;
• •any contraindication of prostate biopsy;
• •Previous prostate biopsy；
• •Previous history of androgen deprivation therapy (ADT), pelvic radiotherapy, and other treatments；
• •Previous history of transurethral prostatectomy (TURP)；