Building of Prognosis Model for Patients With Cirrhosis Based on Sarcopenia Assessed by Deep Learning

Inclusion Criteria

• •Age ≥18 years
• •Diagnosis of liver cirrhosis, meeting at least one of the following criteria:
• •Clinical diagnosis: ICD-10-CM codes K74.100 and K74.607 from our hospital's electronic medical record system
• •Liver biopsy pathology or a combination of clinical, laboratory, and imaging examinations confirming liver cirrhosis: Pathological biopsy criteria: fibrosis bridging between lobules leading to lobular structural disarray, nodular regeneration of hepatocytes, formation of pseudo-lobules
• •Laboratory tests: the presence of at least 2 of the following 4 abnormal indicators suggesting liver cirrhosis:
• •a) Platelet count \< 100×10\^9/L, with no other explainable cause;
• •b) Serum albumin \< 35g/L, excluding malnutrition or kidney disease as other causes;
• •c) International normalized ratio (INR) \> 1.3 or prolonged prothrombin time (PT) (after discontinuation of thrombolytic or anticoagulant drugs for more than 7 days);
• •d)Aspartate aminotransferase to platelet ratio index (APRI) \> 2.
• •Availability of high-quality L3-level CT images