Impact 360 for Healthy Agers

Exclusion Criteria

• •Any neurological disease/disorder diagnosis (Ex: Parkinson's Disease, Multiple Sclerosis, Traumatic Brain Injury, Brain lesion, Stroke, etc)
• •Any chronic medical condition which would affect ability to participate in exercise
• •Any contraindication for exercise based on the Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) and medical clearance form
• •Participants who were told by a medical doctor that they need to be medically supervised for exercise
• •Montreal Cognitive Assessment (MoCA) scores \<21/30
• •Significant cognitive impairment, depression, or eating disorder
• •Any contraindication to MRI scanning; such as implanted metal clips or wires (see list below)
• •Participants currently doing 180 minutes or more of moderate-vigorous intensity exercise per week AND either of the following:
• •Completion of an Mindfulness-Based Stress Reduction course OR; Score \>8/15 in the Mediterranean-Dietary Approaches to Stop Hypertension (DASH) Intervention for Neurodegenerative Delay (MIND) Diet Questionnaire
• •Significant or unstable cardiovascular or respiratory disease
• •Severe/multiple head trauma(s)
• •Subjects who are pregnant or breastfeeding
• •Subjects with a history or major episodes of drug or alcohol abuse
• •Chronic/acute bacterial/viral infection
• •GI cancer
• •Inflammatory bowel disease
• •Exclusion for MRI scanning:
• •Individuals weighing \> 400 lbs (limit of MRI machine)
• •Artificial heart valve
• •Brain aneurysm clip
• •Electrical stimulator for nerves or bones
• •Ear or eye implant
• •Implanted drug infusion pump
• •Coil, catheter, or filter in any blood vessel
• •Orthopedic hardware (artificial joint, plate, screws)
• •Other metallic prostheses
• •Shrapnel, bullets, or other metal fragments
• •Surgery or tattoos (including tattooed eyeliner) in the last six weeks
• •Brain surgery
• •Have a cardiac pacemaker, wires or defibrillator
• •Have had an injury where a piece of metal lodged in the eye or orbit
• •Have a ferromagnetic aneurysm clip