Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Suzhou Sanegene Bio Inc.
With
Innovent Biologics (Suzhou) Co. Ltd.
Age
18–55
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Has body mass index (BMI) ≥18 and ≤30 kg/m\^2 and has bodyweight ≥ 50 kg;
Has Systolic blood pressure (SBP) ≥100 mmHg and ≤150 mmHg and diastolic blood pressure (DBP) ≥65 mmHg and ≤95 mmHg at screening;
You may not be if
Has mental illness, liver and kidney disease, gastrointestinal disease, nervous system disease, or other related systemic diseases that affect the trial;
Has a history of hospitalization or other clinically significant diseases within 1 month before screening, major surgery within 6 months before screening, or other unstable conditions judged by the investigator;
Has a history of orthostatic hypotension or syncope;
Patients with clinically significant abnormalities confirmed by physical examination, 12-lead electrocardiogram, laboratory tests, etc., or those who meet any of the following conditions during screening need to be excluded:
1. Alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin higher than 1.5× upper limit of normal (ULN)
2. Serum creatinine (Cr) higher than ULN
3. Serum potassium higher than 5 mmol/L
4. QT/QTc interval prolongation during screening (QTcF\>450 ms)
Clareo Health | Study of SGB-3908 in Healthy Subjects and Mildly Hypertensive Subjects
