Comprehensive Intervention of Diabetes and Psoriasis Comorbidity Prevention and Control

Exclusion Criteria

• •1. Patients already diagnosed with diabetes.
• •2. Presence of other active skin diseases that may affect the assessment of the condition.
• •3. In severe, difficult-to-control acute or chronic infection locally or systemically.
• •4. Severe systemic diseases; or patients with clinical laboratory indicators falling into any of the following conditions:
• •① Hematology: Hemoglobin (HGB) \< 90g/L; Platelet count (PLT) \< 10010\^9/L; White blood cell count (WBC) \< 310\^9/L; Absolute neutrophil count (NEUT) \< 1.5\*10\^9/L;
• •② Liver function: Alanine aminotransferase (ALT) or Aspartate aminotransferase (AST) exceeding 3 times the upper limit of normal (ULN) or total bilirubin exceeding 1.5 times the upper limit of normal;
• •③ Renal function: Serum creatinine greater than 1.5 times the upper limit of normal;
• •④ Other abnormal laboratory test results judged by the investigator to potentially affect the patient's completion of the trial or interfere with the trial results.
• •5. History of malignant tumors and primary or secondary immunodeficiency or hypersensitivity.
• •6. Underwent major surgery within 8 weeks or will require such surgery during the study period.
• •7. Pregnant or lactating women.
• •8. History of alcoholism, drug abuse, or substance abuse.
• •9. History of severe mental illness or family history thereof.
• •10. Family history of tumors.
• •11. Other reasons deemed inappropriate for participation by the investigator.