Wisconsin Ginseng for Decreasing Cancer Related Fatigue

Inclusion Criteria

• •Age ≥ 18 years
• •Has received or is receiving treatment for a solid-organ malignancy (not hematologic)
• •History of cancer-related fatigue as defined by an average score ≥ 4 over the past 30 days on the numeric analogue scale. Patients can answer questions orally rather than completing worksheet
• •Baseline control of insomnia: Insomnia ≤ 4 on Linear Analogue Scale. Patients can answer questions orally rather than completing worksheet
• •Baseline control of pain: Pain ≤ 4 on Linear Analogue Scale. Patients can answer questions orally rather than completing worksheet
• •Life expectancy ≥ 6 months
• •Eastern Cooperative Oncology Group (ECOG) performance status (PS) 0, 1 or 2
• •Hemoglobin ≥ 10.0 g/dL (patients must not have been transfused in the preceding 90 days to meet this criterion) (≤ 180 days prior to registration)
• •Alanine aminotransferase (ALT) or aspartate transaminase (AST) ≤ 3 x upper limit normal (ULN) (≤ 180 days prior to registration)
• •Creatinine ≤ 1.5 x ULN (≤ 180 days prior to registration)
• •No clinical suspicion of hypothyroidism within 180 days prior to registration \[if clinical suspicion of hypothyroidism exists, a documented thyroid stimulating hormone (TSH) \< 5 milli-international units per liter (mIU/L) is required\]
• •Negative pregnancy test done ≤ 7 days prior to registration, for persons of childbearing potential only
• •Ability to complete questionnaire(s) by themselves or with assistance
• •Provide informed consent