Allogeneic Valve Transplantation

Exclusion Criteria

• •Age \< 30 days
• •Irreversible multisystem organ failure; or additive effects of the multiple systems affected making transplant survival unlikely
• •Progressive systemic disease with early mortality (genetic/metabolic, idiopathic, syndromic)
• •Morbid obesity (BMI\>35)
• •Diabetes mellitus with evidence of end-organ damage
• •Severe chromosomal, neurologic or syndromic abnormalities
• •Immunocompromised condition (DiGeorge, SCID etc.)
• •Active infection
• •History of endocarditis
• •HIV or chronic hepatitis B or C infection
• •Malignancy within 5 years prior to transplant
• •Severe renal or liver failure
• •Inadequate social support for post-transplant management
• •Recent history of illicit drug, tobacco or alcohol abuse despite trials/assistance to stop behavior
• •Evidence of large stroke with high risk for hemorrhagic conversion
• •Heart transplant recipient
• •Patients that are unable to follow-up during the initial 6 month window
• •Patients that are unable to provide medical record authorization for 5 years