Safety and Efficacy of tPBM for Epileptiform Activity in Autism

Exclusion Criteria

• •Significant self-abusive or violent behavior or evidence of suicidal ideation, plan or behavior
• •Severely affected children as defined by CGI-Severity Standard Score = 7 (Extremely Ill)
• •Severe prematurity (\<34 weeks gestation) as determined by medical history
• •Current uncontrolled gastroesophageal reflux disease since GERD can cause movements that appear like seizures
• •Genetic syndromes
• •Congenital brain malformations
• •Any medical condition that the PI determines could jeopardize the safety of the study subject or compromise the integrity of the data.
• •Failure to thrive or Body Mass Index \&lt; 5%ile or \&lt;5%ile for weight (male \&lt;11.2kg; female \&lt;10.8kg by CDC 2000 growth charts) at the time of the study.
• •Concurrent treatment with drug that would significantly interact with treatment.
• •* • Stimulants
• •* • Anti-Psychotics
• •* • Antihistamines
• •Excessive Hair that the caregivers are unwilling or unable to shave or braid.
• •Inability to tolerate the required dosage of tPBM treatment due to sensory issues.