Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance

Exclusion Criteria

• •(1) meet DSM-V criteria for substance use disorders other than tobacco, cannabis, or caffeine,
• •(2) are currently receiving or interested in immediately receiving behavioral treatment or medication for cannabis cessation,
• •(3) current use of any medications that could affect study outcomes,
• •(4) test positive for drugs of abuse (other than cannabis) and/or breath alcohol test at study admission,
• •(5) have a current physical or mental illness judged by the study team to negatively impact participant safety or scientific integrity,
• •(6) are currently pregnant, planning to become pregnant in the next three months or are currently breastfeeding,
• •(7) have a history of clinically significant cardiac arrhythmias or vasospastic disease (e.g. Prinzmetal's angina), or (8) are currently enrolled in another clinical trial or have received any drug as part of a research study within 30 days of study participation.