Safety and Effectiveness of Minimally Invasive Micro Sclerostomy (MIMS®) to Reduce Intraocular Pressure in Open-Angle Glaucoma Which is Not Controlled Despite Polypharmacy

You may be eligible if

• 1. Male or female, ≥ 40 years to ≤ 85 years old
• 2. Inadequately controlled primary open angle glaucoma with screening mean diurnal IOP of ≥ 21 mmHg and ≤ 40 mmHg despite polypharmacy
• 3. Primary open angle glaucoma diagnosis based on:
• 1. Visual field mean deviation of -3dB or worse and
• 2. Glaucomatous optic nerve damage as evidenced by optic disc or retinal nerve fiber layer structural abnormalities documented on slit lamp stereo biomicroscopy or in stereo disc photos
• 4. Presence of healthy, free, and mobile conjunctiva in the target quadrant
• 5. Prior ab interno conjunctival-sparing glaucoma procedures were conducted more than 6 months prior to enrollment (e.g., iStent, Trabectome, gonioscopy-assisted transluminal trabeculectomy \[GATT\])
• 6. Subject is able and willing to attend all scheduled follow-up exams
• 7. Subject understands and signs the informed consent