Red Yeast Rice for Primary Prevention of Hypercholesterolemia

Exclusion Criteria

• •Have received anti-hyperlipidemic drugs or red yeast rice treatment within the past month;
• •Female;
• •Have experienced rhabdomyolysis or abnormal liver function ALT \>72 U/L due to taking red yeast rice;
• •Bleeding diseases, such as abnormal platelets, abnormal coagulation factors, or gastrointestinal tract infection within one month
• •Liver insufficiency ALT \>72 U/L or renal insufficiency eGFR \< 30 mL/min/1.73 m2;
• •Have ever had coronary heart disease, myocardial infarction or cerebrovascular disease;
• •Stressful situations, including hospitalization or surgery within the past or next month, and cancer still being treated;
• •Uncontrolled hypertension (blood pressure ≥160/100 mmHg);
• •Use antibiotics, probiotics or weight-loss drugs for more than 3 consecutive days within 3 months before inclusion in the study;
• •Drug abuse or poor compliance;
• •Use of traditional Chinese medicine in the past month