LCAT (Lecithin Cholesterol Acyl Transferase) Natural History Study

Inclusion Criteria

• •1. Males or Females of any age
• •2. Subjects with:
• •1. a diagnosis of primary LCAT deficiency based on investigator assessment or laboratory results AND/OR
• •2. a genetically confirmed mutation in the LCAT gene who are homozygous or compound heterozygous for LCAT loss-of-function mutations
• •3. Subjects or their legal guardian must be able to comprehend and be willing to provide a signed institutional review board/ethics committee (IRB/EC) approved Informed Consent Form. A waiver of consent will be requested for deceased patients, as determined by local regulatory requirements.