Feeding Tolerance and Growth of Preterm Infants Consuming a Supplement Containing Two Human Milk Oligosaccharides (HMOs)

Exclusion Criteria

• •1. Infant is clinically unstable, for example:
• •1. Infant has hemodynamic instability as evidenced by clinical signs of sepsis, hypotension (MAP \< 5th percentile for age for at least three hours), or is receiving vasopressor drugs
• •2. Infant has received an exchange transfusion within the past 48 hours
• •3. Infant has had an episode of severe asphyxia at birth (PH less than 7.0)
• •4. Infant has signs of necrotizing enterocolitis according to modified Bell staging criteria (stage IIA or higher)
• •2. Major congenital (e.g., heart disease, skeletal dysplasia, chondrodystrophy, gastrointestinal obstruction or atresia) or chromosomal abnormality (e.g., trisomy 21, Turner syndrome)
• •3. Infant has other medical condition that, in the judgement of the investigator, would make the child inappropriate for entry into the study
• •4. Participation in another interventional clinical study that may interfere with the results of this study