Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Hospital Mutua de Terrassa
Age
45–any
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
MC and Chronic watery diarrhea patients
1. Women ≥ 45 years old / Men ≥ 60 years old.
2. Patient with chronic watery diarrhea without blood with ≥2 liquid stools per day for minimum 3 times a week and lasting at least 1 month.
3. Blood analysis values within normality, with negative celiac disease serology and absence of acute phase reactants (normal C-reactive protein) and normal thyroid hormones. Calprotectin values may be elevated.
4. Signing of the informed consent.
Patients with Advanced Colon Adenomas
1. Age between 50 and 70 years.
2. Population screening participants with polyps with a crypt pattern of adenomatous appearance and polyp size of ≥10mm, or patients referred for endoscopic treatment of advanced adenomas.
3. Signing of the informed consent.
Healthy controls
1\. Age between 50 and 70 years. 2. Participants in the population screening with normal colonoscopy (without endoscopic alterations except presence of \< 5 polyps (all less than 10mm) and/or colonic diverticulosis (except multiple diverticula in the sigma)). 3. Signing of the informed consent.
You may not be if
1. Pregnancy or breastfeeding.
2. Patients who have received antibiotic, probiotic or prebiotic treatment in the 3 months prior to the study. 3. Patients who have traveled to developing or underdeveloped countries in the 3 months prior to the start of the study.
4\. Patients who have received immunosuppressants and corticosteroids in the 3 months prior to the start of the study.
5\. Patients who have received radiotherapy and/or chemotherapy in the 6 months prior to the start of the study.
6\. Consumption of herbal products. 7. Bacterial or parasitic intestinal infection (including Blastocystis hominis).
8\. History of inflammatory bowel disease or celiac disease. 9. Previous gastrointestinal surgery (excluding appendectomy or inguinal hernia repair).
10\. Incomplete colonoscopy or lack of biopsies of the right, transverse and left colon.
11\. Unsatisfactory preparation for a complete examination (Boston scale \<6, any segment \<2).
12\. Inability to understand the instructions involved in participating in this study
Clareo Health | Mucosa Adherent Intestinal Microbiome in Microscopic Colitis and Colorectal Cancer
