smoking more than 10 cigarettes (or equivalent) per day or smoking history ≥10 pack-years.
Any medical or psychiatric condition or laboratory abnormality.
Stopped receiving pulmonary hypertension chronic general supportive therapy 90 days prior to Day 1.
Pulmonary capillary wedge pressure \> 15 mmHg on right heart catheterization (RHC) conducted during Screening.
History of severe allergic or anaphylactic reaction or hypersensitivity to recombinant proteins or excipients in investigational product.
Major surgery within 8 weeks prior to randomization.
Participants who smoke more than 10 cigarettes (or equivalent) per day or has a smoking history ≥10 pack-years.
Clareo Health | A Study to Learn About the Study Medicine Called PF-07868489 in Healthy Adult People and in People With Pulmonary Arterial Hypertension
