Fiber Tolerance Study

Exclusion Criteria

• •1. Presence or history of chronic gastrointestinal disorders (e.g. stomach ulcers, ulcerative colitis, Crohn's disease) or history of abdominal surgery with resection of the bowel (small or large intestine).
• •2. Presence of other medical conditions where gastrointestinal function often/probably is affected, such as:
• •1. autoimmune diseases (e.g. diabetes mellitus type I, multiple sclerosis, systemic lupus erythematosus).
• •2. eating disorders (e.g. anorexia nervosa, bulimia nervosa, binge eating disorder).
• •3. intestinal/gastrointestinal disorder due to a stroke.
• •3. Chronic diseases (including but not limited to hypertension, dyslipidaemia, type 2 diabetes mellitus, thyroid disorders) that cannot be controlled with the use of medication/therapy.
• •4. Severe acute liver disease or chronic liver disease.
• •5. Severe or chronic kidney disease or need for hemodialysis.
• •6. Colonoscopy, irrigoscopy or other bowel cleansing, or other surgical procedures related to the gastrointestinal tract (eg. colon polypectomy, appendectomy) or for which use of systemic antibiotics within 1 month before the screening is required or scheduled during participation in the study.
• •7. Use of enemas, laxatives, antacids, proton pump inhibitors, prokinetics (e.g. metoclopramide, drugs that affect motility), digestive enzymes, narcotic/morphine analgesics within 1 week prior to screening or intended use during participation in the study.
• •8. Following a vegetarian or vegan diet.