About Pricing FAQs Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

Exparel vs Block for ACL Reconstruction | Clinical Trials | Clareo Health

Back to clinical trial search

Enrolling By InvitationPhase 4NCT06006624

Exparel vs Block for ACL Reconstruction

Liposomal bupivacaine or Exparel (Pacira Biosciences) is a long-lasting nonopioid analgesic that was initially utilized as an infiltrative agent but has more recently become U.S. Food and Drug Adminis...

Lead sponsor: Rothman Institute Orthopaedics•1 U.S. locations•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Sponsors

Lead Sponsor

Rothman Institute Orthopaedics

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Paticipants with ACL rupture amenable to reconstruction with BTB autograft identified in clinic by one of 4 different surgeons
•Primary ACL Reconstruction with Autograft +/- Partial meniscectomy +/- Lateral extra-articular tenodesis
•Age 18 and older
•English speaking
•Ability to complete surveys by phone or in person
•Ability to provide informed consent

Exclusion Criteria

•Revision cases
•Multi-ligamentous knee injuries
•Cartilage or meniscal procedures that prevent adherence to immediate weight bearing and range of motion rehab protocol
•ACL reconstruction utilizing non-bone-patellar tendon-bone autografts
•Allergies to study medications
•Non-English speakers
•Known alcohol or narcotic abuse history
•Existing contract with a pain specialist due to underlying preoperative pain syndrome
•Preoperative opioid use within the 3 months prior to surgery

Related studies

Preoperative Sleep Quality and Postoperative Outcomes in Breast Surgery

NCT07547774 · Breast Cancer, Postoperative Pain, and more

Clinical and Biomechanical Outcomes of Anterior Cruciate Ligament (ACL) Reconstruction Associated With Lateral Extra-articular Tenodesis (LET)

NCT07049484 · ACL Reconstruction, Tenodesis, and more

RECRUITINGPhase 3

RADA16 for Adult Tonsillectomy

NCT07060495 · Postoperative Pain

Investigation of the Effects of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block on Perioperative Analgesia Management in Patients Scheduled for Mastectomy

NCT07510269 · Postoperative Pain, Nerve Block, and more

Different Hemostatic Agents Used in Partial Pulpotomy on Pulp Survival and Postoperative Pain

NCT07058727 · Efficacy of Hemostatic Agents, Partial Pulpotomy, and more

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: June 21, 2024Terms

Trial snapshot

StatusENROLLING_BY_INVITATION

PhasePHASE4

Enrollment154

Start dateAug 2023

Last updatedJun 21, 2024

Condition

ACL Postoperative Pain

Locations shown

Rothman Orthopaedic Institute

Philadelphia, Pennsylvania

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 21, 2024Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions