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RECRUITINGNCT05969574

Is Decreased Ovarian Reserve Related to an Increased Number of Previous Early Miscarriages?

This study aims to explore the potential correlation between decreased ovarian reserve and previous history of early miscarriage.

Lead sponsor: ART Fertility Clinics LLC•3 locations•View source on ClinicalTrials.gov

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Contacts

Barbara Lawrenz, PhD

CONTACT

+971 800 337845489 [email protected]

Jonalyn Edades, RN

CONTACT

+971 800 337845489 [email protected]

Sponsors

Lead Sponsor

ART Fertility Clinics LLC

By investigating the prevalence of low ovarian reserve (LOR) in populations with specific reproductive histories (such as recurrent pregnancy loss, G0, and ectopic pregnancy), as well as the aneuploidy rates of embryos produced with Preimplantation Genetic Testing for Aneuploidies (PGT-A), Investigators can better understand how LOR impacts fertility outcomes in these populations. This information can be used to inform clinical decision-making, such as whether participants with LOR should consider alternative or whether they would benefit from additional interventions to improve ovarian function. Ultimately, by improving our understanding of how LOR impacts fertility outcomes in specific populations, Investigators can help to improve the overall success rates of infertility treatment, reduce anxiety, and distress, and help participants achieve goals of becoming parents.

Age

All ages

Sex

FEMALE

Healthy Volunteers

No

Inclusion Criteria

•1\. All participants with at least 1 previous pregnancy, who are assessed in one of our clinics (ART Fertility Clinics Abu Dhabi, Al Ain, Dubai)

Exclusion Criteria

•1. Severe male factor (azoospermia, cryptozoospermia, severe oligoasthenoteratozoospermia (OAT))
•2. Severe Endometriosis and adenomyosis based on positive anamnesis or ultrasound performed in our center during the first consultation
•3. Uterine abnormalities (e.g. fibroids, different degrees of uterine septum), diagnosed by ultrasound
•4. History of ovarian surgery, chemotherapy, or radiation therapy
•5. Known genetic disorder or chromosomal abnormality
•6. BMI \>40Kg/m2
•7. Currently using hormonal contraception or hormone replacement therapy

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: February 19, 2025Terms

Trial snapshot

StatusRECRUITING

Phase—

Enrollment2,059

Start dateSep 2023

Last updatedFeb 19, 2025

Condition

Infertility, Female Miscarriage Miscarriage, Recurrent IVF

Locations shown

ART Fertility Clinics LLC

Abu Dhabi, Abu Dhabi Emirate

ART Fertility Clinics Al Ain

Al Ain City

ART Fertility Clinics Dubai

Dubai

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 19, 2025Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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