Optimizing Phototesting and Investigating Photobiology of Visible Light

Exclusion Criteria

• •Recent history of vitiligo, melasma, and other disorders of pigmentation with the exception of post-inflammatory hyperpigmentation
• •History of relevant skin conditions such as atopic dermatitis, eczema, or sunburn on any part of the body
• •History of photodermatoses or photosensitivity disorders
• •History of melanoma or non-melanoma skin cancers
• •Use of tanning parlors or exposure of the irradiated sites to sun light during the duration of the study
• •Use of topical or systemic treatment that is likely to interfere with assessment, study results, or pose safety concerns
• •Subjects with a tendency to bleed excessively
• •Known allergies to anesthetics (lidocaine) or anaphylaxis treatment (epinephrine)
• •History of hypertrophic scarring or keloid formation
• •Use of any photosensitizing medication within the visible light range or additional medication at the discretion of the investigator \[examples include - but not limited to - thiazide diuretics, regular use of NSAIDs, hydroxychloroquine, or voriconazole
• •A woman who is lactating, pregnant, or planning to become pregnant