For the case group (MD patients), subjects with moderate or severe major depression, without severe suicide ideation, as characterized by the Patient Health Questionnaire (PHQ)-9 index (values of 9 or greater) and by the Structured Clinical Interview for DSM-5 - (SCID) will be selected.
For the control group, subjects without mental health pathologies identified by SCID, who present an PHQ-9 index of 5 or below will be included as controls.
You may not be if
Pregnant or breastfeeding women.
Diabetes mellitus.
Chronic conditions: HIV infection, chronic intake of NSAIDs.
Comorbidity with other mental disorders: eating disorders, borderline personality disorders, bipolar disorders, schizophrenia and related disorders, and/or any mental serious disease other than major depression.
Severe suicide ideation.
Patients who had received periodontal treatment for periodontitis in the last year.
Presence of necrotizing periodontal diseases.
Presence of less than three teeth per quadrant.
Antibiotic use in the last 6 months prior to the study.
Clareo Health | Relationship Between Major Depression and Periodontal Diseases
