1. History of severe somatic or brain organic diseases and craniocerebral trauma;

2. Abnormal brain structure or any MRI contraindications were found by magnetic resonance examination;

3. Those who do not cooperate or cannot effectively complete the experiment;

4. Drug, alcohol or other psychoactive substance abusers;

5. Pregnant, lactating or planned pregnancy.

6. Severe suicidal ideation and behavior

7. ECT or rTMS treatment was performed within six months

Neuronavigation rTMS to Improve Depressive Episodes of Bipolar Disorder in Adolescent