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18F-FAPI PET Imaging in Pancreatic Adenocarcinoma | Clinical Trials | Clareo Health

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COMPLETEDNANCT05884463

18F-FAPI PET Imaging in Pancreatic Adenocarcinoma

To explore the potential efficacy of 18F-FAPI-04 PET/CT for PDAC tumour staging and compare the results with those obtained using 18F-FDG PET/CT.

Lead sponsor: Zhejiang University•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Zhejiang University

Accurate diagnosis and staging are crucial for selecting treatment for patients with pancreatic ductal adenocarcinoma (PDAC). The desmoplastic responses associated with PDAC are often characterised by hypometabolism. Here we investigated 18F-fibroblast activation protein inhibitor (18F-FAPI-04) positron emission tomography/computed tomography (PET/CT) in evaluation of PDAC, and compared the findings with those obtained using (18F)-fluorodeoxyglucose (18F-FDG).

Age

18 - 80 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•patients who were suspected to have PDAC by radiological imaging patients who underwent paired 18F-FAPI-04 PET/CT and 18F-FDG PET/CT for metastasis screening, recurrence confirmation, or tumour staging patients who were willing to participate in clinical trials and signed an informed consent form.

Exclusion Criteria

•patients with a history of severe contrast allergy pregnant patients patients who were not pathologically diagnosed as showing PDAC.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: June 1, 2023Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment62

Start dateApr 2021

Last updatedJun 1, 2023

Condition

18F-FAPI 18F-FDG Pancreas Adenocarcinoma Diagnosis Staging

Locations shown

the First Affiliated Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 1, 2023Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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