Lead Sponsor

Saint-Joseph University

Age

35 - 74 years

Sex

ALL

Healthy Volunteers

Yes

•Absence of systemic or osseous disease that may impair peri-implant healing
•Age ≥ 21 years
•Acceptable oral hygiene
•Presence of both adjacent teeth
•Absence of acute infection in the treated area
•Absence of periodontal pockets \> 3mm at the concerned site
•Absence of pre-operative defect at the buccal bone wall (dehiscence or fenestration)
•Per-operative integrity of the osseous and gingival structures (during tooth extraction)
•Light or non-smoker (\<10 cigarettes per day)

•Myocardial infarction within the past 6 months.
•Poorly controlled diabetes (HBA1c \> 7.5%).
•Coagulation disorders.
•Radiotherapy to the head/neck area within the past two years.
•Present or past treatment with intravenous bisphosphonates.
•Immunocompromised patients.
•Psychological or psychiatric problems.
•Alcohol or drug abuse.
•Poor oral hygiene and motivation (full mouth plaque score \> 30% and/or full mouth bleeding score \> 20%).
•Uncontrolled periodontal disease.

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