Lead Sponsor

Visirna Therapeutics HK Limited

Age

18 - 55 years

Sex

ALL

Healthy Volunteers

Yes

•Women of child bearing potential must have a negative pregnancy test, cannot be breastfeeding and must be willing to use contraception
•BMI 18.0\~28.0 kg/m2
•Willing to provide written informed consent and to comply with study requirements
•On a stable diet for at least 4 weeks with no plans to significantly alter diet or weight over course of study
•TG\> 100 mg/dL
•LDL-C\> 70 mg/dL

•Clinically significant health concerns
•Regular use of alcohol within one month prior to screening
•Recent (within 3 months) use of illicit drugs
•Female with pregnancy or breastfeeding
•QTcF\>450 ms in ECG
•Donation or loss of whole blood more than 400 ml prior to administration of the study treatment