Age

18–70

Sex

ALL

Healthy volunteers

Not accepted

Patients with PA, confirmed by an elevated aldosterone/renin ratio (ARR) and an intravenous salt loading test.
The patient has provided written informed consent authorisation before participating in the study.
The patient is 18 to 70 years of age at the time of consent.

Refusal by the patients to undergo 68Ga-PentixaFor PET/CT, AVS, CT, or adrenalectomy.
Suspicion of familial hyperaldosteronism type 1 (FH-1) or type 3 (FH-3).
Suspicion of adrenocortical carcinoma.
Severe comorbidity potentially interfering with treatment or health-related quality of life.
Patients need to take drugs that interfere with clinical research.
Any medical condition present that in the opinion of the investigator will affect patients clinical status.
Pregnancy or lactation.
Estimated glomerular filtration rate \<40mL/min/1.73m2.
Interfering treatment in between 68Ga-PentixaFor PET/CT and AVS.

CXCR4 Targeted PET Imaging in APA Preoperative Localization Diagnosis