Treatment of Gingival Recession Defects Using Platelet-Rich Fibrin With an Allogenic Dermal Matrix

Exclusion Criteria

• •Contraindications for undergoing periodontal surgery
• •Teeth with more than Grade II mobility, or furcation involvement of Class III
• •Patients pregnant or attempting to get pregnant (self-reported), or nursing women
• •Untreated/active periodontitis, or other untreated acute infections at the surgical site
• •Untreated malignancies at the surgical site
• •Persistence of uncorrected gingival trauma from traumatic toothbrushing
• •Presence of severe tooth malposition, rotation or clinically significant super-eruption
• •Self-reported current smoking more than 10 cigarettes/day or pipe or cigar smoking, or active tobacco chewing, or chronic vaping
• •Patients with any known history of blood disorders or complications such as abnormal concentration of thrombin and factor XIII in plasma, or hemophilia
• •Patients with significant co-morbidities, such as obesity, uncontrolled diabetes, immunosuppression, severe endocrine-induced bone diseases, signs of malnourishment, those receiving immunosuppressive therapy, poor tissue oxygenation or perfusion, and pre- or post-operative radiation
• •Patients with known sensitivity to Polysorbate 20, Cefoxitin, Lincomycin, polymyxin B, Vancomycin