A Study to Evaluate Plasma Gelsolin in Healthy Volunteers

Exclusion Criteria

• •1. Pregnant or lactating women
• •2. Acute illness during the month prior to screening
• •3. Circumstances that may require any medications (including prescription medication, over-the-counter medication, vitamins, or supplements) during the during the inpatient days of the study other than acetaminophen
• •4. Hospitalization during the year prior to screening
• •5. History of cancer or treatment with systemic chemotherapy or radiation therapy at any time
• •6. Transplantation of hematopoietic or solid organs
• •7. History of diabetes mellitus; myocardial infarction, angina, or other cardiovascular disease; stroke or cerebrovascular disease; chronic obstructive pulmonary disease (COPD) or asthma; deep vein thrombosis (DVT)/pulmonary embolism (PE); liver or kidney disease; clinically significant psychiatric condition; or active or chronic infection
• •8. Receipt of blood products during the year prior to screening
• •9. Chronic mechanical ventilation or dialysis
• •10. Any clinically significant abnormalities in clinical chemistry, hematology, or urinalysis results as judged by the Investigator
• •11. Any clinically significant abnormalities of vital signs, EKG or physical examination findings as judged by the Investigator
• •12. Positive results for recreational drugs during screening
• •13. Any other condition deemed by the Investigator as possibly interfering with the conduct of the study