Study Evaluating the Effect of a Specific Trace Metal Complex Versus Placebo on the Severity of Apnea in Patients With Obstructive Sleep Apnea Syndrome

Exclusion Criteria

• •patient previously treated for OSA by continuous positive airway pressure or mandibular orthosis
• •obesity (body mass index \> 30 kg/m2)
• •pregnant or post-pregnancy women less than 6 months old or of childbearing age without an effective method of contraception
• •respiratory, cardiac, hepatic or renal failure
• •active cancer or history of cancer
• •alcohol abuse
• •antidepressant intake
• •use of compression stockings
• •intake of product or supplementation enriched with trace metals and/or trace elements and/or mineral salts and/or vitamins.
• •taking any type of psychotropic medication
• •previous intake of trace elements to treat OSA