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COMPLETEDNCT05750927

Aortic Stenosis With COmplex PCI (ASCOP) Features Retrospective Registry on Contemporary Management and Outcomes

To describe the prevalence and clinical features of patients with severe aortic stenosis undergoing TAVI and concomitant clinically indicated, complex and/or high-risk PCI

Lead sponsor: Niguarda Hospital•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Niguarda Hospital

The aims of this study are: * to describe the prevalence and clinical features of patients with severe aortic stenosis undergoing TAVI and concomitant clinically indicated, complex and/or high-risk PCI * to depict the different possible strategies that are currently employed in this context and to retrospectively analyze outcomes * to investigate predictors of better outcomes

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•1. Severe, symptomatic aortic stenosis with an indication to TAVI
•2. Concomitant, stable CAD with an indication to complex PCI, as anticipated by angiography, defined as follows (one or more features)
•1. Left-main (LM) CAD or proximal left anterior descending (LAD) / left circumflex (LCx) lesions requiring LM-PCI
•2. Three-vessel disease
•3. Last remaining vessel
•4. Bifurcation PCI (proximal bifurcation)
•5. Severely calcified lesions requiring calcium plaque modification (rotational/orbital atherectomy, intravascular lithotripsy, scoring or cutting balloon)
•6. Lesion length \> 30 mm
•7. Severely depressed Left ventricular function requiring mechanical circulatory support (intra-aortic balloon pump - IABP, Impella, Extracorporeal Membrane Oxygenation - ECMO

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: March 21, 2024Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment100

Start dateDec 2022

Last updatedMar 21, 2024

Condition

Aortic Valve Stenosis Transcatheter Aortic Valve Replacement Angioplasty, Balloon, Coronary Coronary Artery Disease

Locations shown

ASST GOM Niguarda

Milan

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 21, 2024Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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