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Active Not RecruitingPhase 3NCT05748483

Comparative Study of Oral Atogepant Versus Oral Topiramate to Assess Adverse Events in Adult Participants With Migraine

A migraine is a moderate to severe headache on one side of the head that may be accompanied by throbbing, nausea, vomiting, sensitivity to light and sound, or other symptoms. The main goal of the stud...

Lead sponsor: AbbVie•81 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

AbbVie

Age

18 - 80 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Documented history of migraine (with or without aura) for \>= 12 months prior to screening (Visit 1).
•History of \>= 4 migraine days per month who require preventive treatment of migraine and are eligible for conventional migraine prophylaxis.

Exclusion Criteria

•Have used topiramate or atogepant in the past.
•Have clinically significant cardiovascular, cerebrovascular, hematologic, endocrine, pulmonary, renal, hepatic, gastrointestinal, or neurologic disease.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 25, 2025Terms

Trial snapshot

StatusACTIVE_NOT_RECRUITING

PhasePHASE3

Enrollment545

Start dateOct 2023

Last updatedMay 25, 2025

Condition

Locations shown

Medizinische Universitaet Wien /ID# 247119

Vienna, State of Vienna

Medizinische Universitaet Innsbruck /ID# 247213

Innsbruck, Tyrol

Konventhospital Barmherzige Brueder Linz /ID# 247217

Linz, Upper Austria

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 25, 2025Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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