Efficacy and Safety of Apalutamide in Combination With 89Sr as Neoadjuvant Therapy in Prostate Cancer With ≤10 Bone Metastases

Inclusion Criteria

• •1. Prostate cancer confirmed by pathological findings;
• •2. Bone metastasis confirmed by bone scan, the number of bone metastases ≤10
• •3. Agreement to undergo laparoscopic radical prostatectomy + pelvic lymphadenectomy;
• •4. ECOG score of 0 - 1
• •5. Agreement to undergo preoperative and postoperative endocrine therapy and 89Sr radionuclide therapy;
• •6. Voluntary signing of an ICF for the clinical trial