Patients diagnosed with bronchiectasis (according to the Chinese consensus, patient's previous chest CT examination must show bronchiectasis) or COPD (according to GOLD 2022).
Patients with age ≥18 years old.
Written informed consent.
You may not be if
Pregnancy or lactation, or those without taking effective contraceptive measures
Subjects with a history of mental illness or suicide risk, with a history of epilepsy or other central nervous system disorders
Subjects with a history of alcohol or illicit drug abuse
Subjects with any of the following pulmonary diseases: active tuberculosis, pulmonary embolism, pneumothorax, multiple huge bullae, uncontrolled asthma, acute exacerbation of chronic bronchitis or extremely severe COPD
Diagnosis of chronic gastrointestinal disease, heart disease, diabetes, severe renal insufficiency (GFR \< 30ml/min) or immunodeficiency
Participated in any interventional clinical trial within 3 months before enrolment.
Poor compliance or inability to cooperate as judged by the doctor
Clareo Health | Multi-omics Studies of Host-microbiome Interaction in Chronic Obstructive Pulmonary Disease and Bronchiectasis