Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Indira IVF Hospital Pvt Ltd
The Research question(PICO) addressed is Does NC-FET decreases the incidence of preeclampsia in patients undergoing frozen embryo transfer as compared to AC-FET . The hypothesis taken is NC-FET will decrease the incidence of preeclampsia compared to AC-FET. The sample size is taken as 3026 (1513 per arm). The Primary Objective is to compare the proportion of preeclampsia in women with a viable pregnancy with natural cycle protocol to artificial cycle protocol when practicing frozen embryo transfer. The study outcome of the proportion of preeclampsia after 20 weeks of gestation or 6 weeks post-delivery. There are two arms-Arm 1 Active Comparator: Natural Cycle and Arm 2 control: Artificial Cycle FET. The Randomization is done through Random Allocation as per computer generated sequence. The Blinding/masking is done Open labeled. The Study Duration is from Feb 2023 to Jan 2025. Participation Duration is 10 months.
Age
21–45
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Endometrial preparation with Hormone replacement therapy/ Natural cycle.
Age 21-45 years following an autologous IVF cycle (with or without preimplantation genetic testing for aneuploidy)
BMI \> 18 and \< 30 kg/m2
Endometrial thickness ≥ 7 mm after estrogen therapy or on the day of ovulation
