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COMPLETEDNCT05708547

Role of Mitophagy in Myeloid Cells During Coronary Atherosclerosis.

Atherosclerosis (deposition of a plaque essentially composed of lipids on the artery walls) is a frequent condition and is a leading cause of death worldwide. In addition to the long-established risk ...

Lead sponsor: Centre Hospitalier Universitaire Dijon•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Centre Hospitalier Universitaire Dijon

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•\- Person who provides oral consent
•Group 1:
•\- Patient scheduled for cardiac bypass surgery (isolated procedure) with extracorporeal circulation
•Group 2:
•Patient scheduled for valve ou ascending aorta surgery with extracorporeal circulation
•No coronary lesion
•No peripheral arterial disease (limbs, carotids, aortic aneurysm)

Exclusion Criteria

•Person not affiliated with national health care system
•Medication that alters mitochondrial function (Chloroquine, hydroxychloroquine, rapamycin, carbamazepine, resveratrol, sildenafil)
•Person under a legal protection measure (curatorship, guardianship, tutorship)
•Pregnant, parturient or breastfeeding women
•Major unable to express consent
•Minor

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: November 21, 2025Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment61

Start dateNov 2023

Last updatedNov 21, 2025

Condition

Coronary Atherosclerosis

Locations shown

Chu Dijon Bourgogne

Dijon

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 21, 2025Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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