Effectiveness of Outpatient Intravenous Diuretic Therapy for Treatment of Worsening Heart Failure (OUTPATIENT-WHF)

Exclusion Criteria

• •1. Managing clinician without equipoise for initial outpatient treatment strategy versus initial hospitalization-based treatment strategy for heart failure, and decline to accept randomization.
• •2. Patient without equipoise for initial outpatient treatment strategy versus initial hospitalization-based treatment strategy for heart failure, and decline to accept randomization.
• •3. History of left ventricular assist device or heart transplantation
• •4. End-stage kidney disease requiring chronic dialysis therapy
• •5. New diagnosis of heart failure
• •6. Pregnant or breast-feeding
• •7. Fever \>101.0 degrees Fahrenheit at screening
• •8. Any other condition that in the judgment of the investigator would jeopardize the patient's compliance with the study protocol