Prospective cohort study of patients with heart failure with reduced ejection fraction that are referred for diagnostic right heart catheterization as part of their evaluation for candidacy for advanced heart failure therapies.
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Adults age 18 years or older
Heart failure with reduced ejection fraction (\<40%)
referred for RHC at our centre for evaluation of candidacy for advanced HF therapies.
You may not be if
Severe valvular or complex congenital heart disease Short-term mechanical circulatory support for progressive cardiogenic shock (e.g. extracorporeal membrane oxygenation) Acute coronary syndrome or revascularization occurred within 7 days prior to the RHC.
Pregnant or breast-feeding Known hypersensitivity to sodium nitroprusside Advanced liver dysfunction Reduced capacity or inability to provide informed consent
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