Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
CMC Ambroise Paré
Age
18–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Adult female patients requiring start of ribociclib based therapy for a breast cancer in their standard of care, as per their summary of product characteristic's indications
Association with hormone-based therapy in combination is authorized (aromatase inhibitors or fulvestrant)
Able to provide an informed consent
You may not be if
Any allergy or contra-indication to ribociclib as mentioned in their as summary of product characteristic's
Patients presenting a condition precluding accurate QTc measurements on electrocardiogram, i.e paced ventricular rhythm, multiples premature ventricular or supra-ventricular contractions, ventricular tachycardia, supraventricular arrhythmia (including atrial fibrillation, flutter or junctional rhythm)
Patients with an atrial pacing and sinus dysfunction
Patients presenting a contra-indication for ECG measurement, or with a device rendering ECG measurements impossible (i.e. Diaphragmatic pacing)
Patients presenting a contra-indication to ribociclib start; including association with prohibited drug potentializing the risk of TdP
