Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
With
VU University of Amsterdam
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Radiographically (CT or EUS) distal malignant bile duct obstruction
Histology or cytology proven malignancy of the primary tumour or metastasis; onsite cytology evaluation after EUS guided fine-needle sampling that is highly suspected of a malignancy suffices
Indication for biliary drainage; in case of a resectable tumour this should be discussed during a clinical multidisciplinary meeting
Written informed consent
You may not be if
Age \< 18 year
Surgically altered anatomy after previous gastric, periampullary or duodenal resection
Cancer extending into the antrum or proximal duodenum
Extensive liver metastases
WHO performance score of 4 (in bed 100% of time)
Uncorrectable coagulopathy, defined by INR\>1.5 or platelets \< 50 x 10\^9/L\*
Clinically relevant gastric-outlet obstruction
Unable to complete sign informed consent
* Inclusion is allowed after corrective treatment measures are taken, according to local protocol and treating physician.
Clareo Health | EUS-guided Choledochoduodenostomy for Primary Drainage of Malignant Distal Biliary Obstruction
