Fontan-Sprechstunde

In particular, the following points will be scientifically analyzed: 1. The development of lymphatic drainage disorders (7-9) 2. The cellular changes of the immunological system and metabolome (10) In addition to the clinical routine, weight-adapted EDTA blood for the isolation of peripheral blood mononuclear cells (PBMCs) for the scientific investigation of immunological changes and serum for the analysis of the metabolome will be examined at three times (Figure 1: Times 2, 4, 7) as part of a routine blood sample (10). 3. The recording and treatment of psychological, social and developmental abnormalities with the help of standardized questionnaires. 4. The evaluation of special sonography examinations of the liver and kidney in the long-term course, as well as their treatment. 5. The assessment of the hemodynamic peculiarities and the classification with regard to Cardiac function in the long-term course of patients with Fontan circulation. 6. The assessment of various laboratory parameters as risk parameters for the development of complications. 7. The recording of cardiopulmonary performance in the long-term course and its ability to be influenced by education regarding sporting activity and the handing over of an individualized training plan. 8. The influence of physical activity on possible complications of Fontan circulation. 9. The influence of early psychological, nutritional, or social intervention in the event of abnormalities on later complications of Fontan circulation.