Patient able to give written informed consent, - Presenting a major depressive episode defined according to DSM V criteria, - Presenting a MADRS score ≥ 20 - Able to understand all study procedures and follow-up
You may not be if
\- Inability to wear the wearable monitor for the duration of the study (6 months)
Patient with a severe medical condition at the discretion of the investigator (neurological, rheumatological, etc.)
Resistant depression
Chronic depression, dysthymia
Depression with psychotic features not congruent with mood, schizophrenia disorder
Depression with catatonic features
Substance use disorder in the last 6 months
Extreme sports during the conduct of the study
Pre-existing skin infection at the wearable monitor site
Pregnant or lactating woman
Participation in another drug or medical device study
