ZonMw: The Netherlands Organisation for Health Research and Development
Age
18–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
≥ 18 years of age
Diagnosis of PCOS according to the Rotterdam consensus criteria and confirmed by a gynaecologist
A viable singleton pregnancy confirmed by ultrasound
Being able to initiate the use of study supplements between 8+0 and 16+0 weeks gestational age
Ability to understand Dutch or English
Ability to provide written informed consent
You may not be if
Diagnosis of pre-existent type-1 or 2 diabetes mellitus
Pre-existent renal failure, defined as an estimated glomerular filtration rate (eGFR) less than 50 ml/min/1.73m2
Use of myo-inositol supplements, other insulin-mimetics, hypoglycaemic agents (e.g. metformin) and/or systemic steroids, that cannot be discontinued at the time of inclusion
Clareo Health | MYPP-trial: Myo-inositol Supplementation to Prevent Pregnancy Complications in Women With Polycystic Ovary Syndrome.
