PRIMARY OBJECTIVE:
I. To improve antibiotic stewardship (reducing duration of peri-operative prophylactic antibiotic regimen, reducing administration of broad-spectrum antibiotic) by providing surgical team with rapid Oxford Nanopore (ONT) sequencing data in the early post-operative setting.
SECONDARY OBJECTIVE:
I. To reduce the cost of care through reduction in surgical site infection (SSI) and improved antibiotic stewardship.
OUTLINE: Patients are randomized to 1 of 2 arms.
ARM I: Patients undergo the collection of bile samples during standard of care surgery. Samples undergo routine laboratory testing.
ARM II: Patients undergo the collection of bile samples during standard of care surgery. Samples undergo nanopore sequencing and routine laboratory testing.
After completion of study, patients' medical records are reviewed for 30 days.
