Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome.

Inclusion Criteria

• •Criteria for the Observer Reported Outcomes (ObsRO) cohort of the study:
• •1. Parents/guardians must be able to read and understand English;
• •2. Parents/guardians must be caring for a child (ages 2-11.999) with a medically documented diagnosis of idiopathic (primary) Nephrotic Syndrome (NS) or primary or monogenic NS associated kidney disease. Populations with Primary NS Conditions: Focal segmental glomerulosclerosis (FSGS), Minimal Change Disease (MCD), Immunoglobulin M (IgM) Nephropathy, Membranous Nephropathy (MN), and childhood - onset nephrotic syndrome not biopsied;
• •3. The child must have a current NS-associated edema
• •4. The child must have native kidney function
• •5. Parents/guardians must provide informed consent.
• •1. ≥8 years of age
• •2. Able to read and understand English
• •3. Primary (idiopathic) kidney disease that causes NS or monogenic NS associated kidney disease.
• •i. Populations with Primary Nephrotic Syndrome (NS) Conditions include: FSGS, MCD, IgM nephropathy, MN, and childhood - onset nephrotic syndrome not biopsied
• •4. Current NS-associated edema
• •5. Kidney function with most recent estimated Glomerular Filtration Rate (eGFR) \> 25 ml/min/1.73m2
• •6. Informed Consent: For patients ≥8 to \<18 years of age: a parent or legal guardian provide informed consent and the patient must provide assent. Patients ≥18 years of age must provide informed consent.