150 patients with established or probable liver cirrhosis at the Department of Gastroenterology and Hepatology at Linköping University Hospital, as well as collaborating hospitals; District Hospital in Eksjö and County Hospital in Jönköping, will be included in the study. The study includes four visits every six months (in patients with LI-RADS 3 five visits will be performed); each patient participates actively in the study during a time period of approximately 24 months. All study visits are scheduled in conjunction with clinical routine visits.
During each study visit the following is performed:
* A detailed clinical work-up
* Assessment of medical history or changes in health status since last visit
* FibroScan
* Magnetic resonance (MR) examination
* Comprehensive blood panels and blood samples for research
* Muscle function and mobility assessments (SPPB and hand grip strength).
* Quality of life assessment (EQ-5D-5L, QLDQ-cirrhosis and SHS-liver).
* Hepatic encephalopathy assessment (ANT test).
* Assessment of the development of symptoms
